Viral Core Facility Research Assistant - Ref. IOB021

100%

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research with a mission to drive innovations in understanding of eye diseases and developing new therapies for vision loss. It is a place where your expertise will be valued, your knowledge expanded and your abilities challenged and developed. We are seeking a highly motivated Research Assistant to join the Viral Core Facility.

The main goal of the Viral Core Facility is to produce viral tools for research groups at the IOB. The profile of the Viral Core Facility is service oriented but open-minded for establishment of new technologies and directions. The catalogue of viral vectors includes adeno-associated viruses (AAVs), lentiviruses (LVs), and rabies viruses. The Viral Core Facility Research Assistant will be responsible for generation of vector DNA, production of viral particles, and quality control by performing quantification and efficiency tests of viral particles.

Your position

  • Generation of plasmid DNA using standard cloning techniques and latest recombination techniques.
  • Production of plasmid DNA in bacteria cultures including plasmid purification and characterization.
  • Production of AAV virus particles by using specific cell culture systems.
  • Purification of viral particles.
  • Quantification and efficiency tests of viral particles, including titration in cells cultures, qPCR, viral efficiency test by protein analysis using western blotting (for shRNA or expression vectors).
  • Involvement in lab management and organization.
  • Close collaboration with group members and the IOB groups.

Your profile

  • Biologielaborant/in (or equivalent education) or Bachelor's/Master's Degree (or equivalent) in molecular biology or related field
  • Basic knowledge of cell biology, molecular biology and biological research
  • Enthusiasm to establish and optimize new protocols and techniques
  • Independence in planning, conductance, analysis and troubleshooting standard molecular biology experiments
  • The candidate should be highly organized, detail-oriented and computer skilled
  • Good written and verbal communications skills
  • Fluency in oral and written English

Special conditions

  • Willingness to work under biosafety level 2 (BL2) laboratory condition

We offer you

  • A key position in a dynamic technology platform, working in close collaboration with the IOB research groups
  • Competitive compensation
  • IOB is an equal-opportunity employer with family-friendly work policies

Application / Contact
Interested candidates should submit their application documents (including two referees) as a single PDF file to jobs@iob.chby May 15th, 2019. Please indicate the position you are applying for by writing the reference number (IOB021) on the subject line.

For further information, please visit our website www.iob.ch or contact Josephine Puttkammer (josephine.puttkammer@iob.ch).


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